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More than half of colorectal cancers (CRCs) harbor activating mutations in KRAS or BRAF, yet those cancers are the most refractory to current targeted therapies

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[DOI] [PMC free article] [PubMed] [Google Scholar] 157.Khramtsov V.V., Gillies R.J

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This route provides consistent absorption and suits self-administration

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Figure 7 explains the process of endocytosis and fate of nanoparticle after internalization into cell cytoplasm

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