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Additionally, participants consumed approximately 23 times the recommended daily intake over a period of 10 years

Blunted or impeded therapeutic response to vitamin B12 may be due to such conditions as infection, uremia, drugs having bone marrow suppressant properties such as chloramphenicol, and concurrent iron or folic acid deficiency

The MHRA product information for hydroxocobalamin preparations lists several recognised side effects that patients should be aware of before commencing treatment

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