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doi: 10.1080/15384047.2025.2538962

PNAS Nexus 1, 110
Purified water
Golden JW

Causes and progression factors of liver inflammation Direct damage caused by alcohol metabolites Ethanol metabolism in the liver occurs through three primary pathways: the alcohol dehydrogenase (ADH) pathway in the hepatocyte cytosol, the cytochrome P450 2E1 (CYP2E1) pathway in the endoplasmic reticulum, and the catalase (CAT) pathway in peroxisomes [18]

Methylation issues are very common (up to 40% of patients) and many patients unknowingly supplement with cyanocobalamin which may increase serum levels but will not improve symptoms 5
