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Conversely, TRIM16 promotes its own expression along with that of the autophagy receptor p62 by driving Nrf2 activation under conditions of oxidative stress ( In addition to regulating transcription factor activity, some TRIMs localize to the nucleus and can directly act as transcriptional regulators or co-regulators
[DOI] [PMC free article] [PubMed] [Google Scholar] Jimdjio Kouasseu C, Yang X, Xue Het al

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This understanding provides insight into disease treatment by regulating lipid metabolism to either enhance or inhibit ferroptosis

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Research interest extends to nitric oxide system modulation, neuroprotection, and dopaminergic / serotonergic pathway interactions
