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Research has investigated the mechanisms by which NNMT inhibition might increase energy expenditure, potentially through effects on mitochondrial function or uncoupling protein expression

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Together, our observations that a small molecule NNMT inhibitor can increase NAD + and SAM concentrations in differentiated adipocytes and reduce adiposity in DIO mice, suggest that treatment with an NNMT inhibitor effectively reverses obesity via modulation of the NAD + salvage and SAM-mediated (e.g., polyamine flux) pathways to regulate energy expenditure in the adipose tissue

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Key Characteristics MOLECULAR PROFILE Formula: C 10 H 11 IN 2 (iodide salt) Weight: 286.11 g/mol CAS: 42464-96-0 Structure: Quinolinium small molecule (NNMT inhibitor) PHYSICAL PROPERTIES Form: Yellow to off-white crystalline powder Solubility: Soluble in water and DMSO Purity: 98% (HPLC) Storage: Keep refrigerated 3646 F (28 C) Please check back soon for availability.

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