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Here we developed a sphingolipid-derived PTX nanovesicle (paclitaxome) via covalently conjugating PTX to sphingomyelin, which improved pharmacokinetics and enhanced efficacy in metastatic triple-negative breast cancer and pancreatic cancer female mice and reduced myelosuppression
10.1002/jbt.21770 89 JaiswalS.AnjumM.ThakurS.PandeyP.AryaD.KumarA.et al (2023)
[DOI] [PubMed] [Google Scholar] 13.Rojano-Ortega D
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