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It is commonly used in food, cosmetics, and fragrances as flavoring agent and exerts potent cannabimimetic anti-inflammatory actions including CB2-dependent therapeutic effects in cerebral ischemia (Choi et al., 2013), insulin resistance (Suijun et al., 2014), glutamate neurotoxicity (Horvth et al., 2012), anxiety and depression (Klauke et al., 2014), and AD (Cheng Y