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Standard U100 insulin syringes (1 mL capacity) are appropriate for the volumes used in this protocol (0.300.60 mL per injection)

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doi: 10.1016/j.jinf.2014.05.014 119 KumarGDagurPKSinghPKShankarHYadavVSKatochVMet al

Prior to analysis, samples were treated with 300 mM acetic acid to enable antibody-drug complex dissociation

After a 30-minute incubation on ice, blood samples were collected at various time points post-intravenous 10 mg/kg dose or intraperitoneal 20 mg/kg dose administration of Dihexa dissolved in 75% DMSO