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Levison, Xiaodong Gu, Matthew F

The deficiency of free CoA limits the efficiency of the Krebs cycle in activating anaerobic glucose metabolism (which inhibits pyruvate dehydrogenase activity, which is responsible for the conversion of pyruvate to acetyl-CoA in aerobic glucose metabolism in cells of the human organism), causing an increase in the concentration of toxic lactate in tissues [58,78,79]

[DOI] [PMC free article] [PubMed] [Google Scholar] 538.Wren TAL, Chung SA, Dorey FJ, Bluml S, Adams GB, Gilsanz V

Despite these advancements, inter-individual variability in absorption remains high, and further research is warranted to optimize AX delivery for clinical efficacy

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Improving effect of huperzine A on discrimination performance in aged rats and adult rats with experimental cognitive impairment