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After treatment with deferoxamine (DFO, an iron chelator), the abnormal iron content and sperm defects can be reversed [69, 70]

NAD-driven metabolic activity increases the need for antioxidant protection
Additionally, SLC25A39 expression is induced in brown fat in response to cold 36 , indicating that it may also be regulated by physiological cues

doi: 10.1161/CIRCRESAHA.116.307591 117 HjortebjergRBojsen-MollerKNSoebyMOxvigCMadsbadSFrystykJ

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In fact, glutathione can enhance the effectiveness of these antioxidants by regenerating them after they've neutralized free radicals
