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However, there is very little clinical data backing this up and even less comparing them to less risky and cheaper autologous orthobiologics like PRP

This effect is not limited to specific cell types but can broadly block the pro-inflammatory activation of innate immune cells and amplify anti-inflammatory effect, as demonstrated (87, 93)

Laboratory studies of self-assembling peptides show that hydrophobic content is the dominant driver of gel formation

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In some cases, side effects are less about the peptide itself and more related to improper handling, overdosing, or contaminated sources from unverified suppliers