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As such, acylcarnitines levels in biological samples reflect the metabolism of acyl- groups for energy from various sources and can inform on current metabolic state which is why they serve as biomarkers of metabolic disorders (Rinaldo et al., 2008

There is an ongoing phase 2/3 randomised, double-blind, placebo-controlled trial (NCT06126315) of the biological and clinical effects of acetyl-l-carnitine planning to recruit ~250 patients [88]