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The Tim-AIII-HSP90 complex, in turn, interacts with GPX4, thus inhibiting the function of GPX4, likely by further ubiquitination and degradation of GXP4, and further inducing ferroptosis

Their distinct targets are exactly why the two classes are of interest when studied in combination

Disturbance of oligodendrocyte development, hypomyelination and white matter injury in the neonatal rat brain after intracerebral injection of lipopolysaccharide
This content was prepared by Yeditepe University Hospitals Medical Editorial Board

It is made up of many concentric layers of plasma membrane to make up the myelin sheath around axons

validation, D.I.C