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The absence of tissue growth effects also means AOD-9604 avoids many common side effects of growth hormone therapy including joint pain and swelling from connective tissue proliferation, carpal tunnel syndrome from tissue expansion, edema and fluid retention from protein synthesis and sodium retention, and concerns about growth-promoting effects in individuals with tumor history
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doi: 10.1038/ncomms13084

doi: 10.1016/j.heliyon.2022.e10807 70 HeQ-YLauGKKZhouYYuenS-TLinMCKungH-Fet al

Yang Y, Awasthi YC
NAMPT activity assay A fluorometric assay was performed by RBC using 1 M 50 pM FK866 as an inhibitor positive control
