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The search terms used to obtain the literature for this review included groups of DAs, specific compounds, aquatic environments, and cross/co-resistance for antibiotic resistance genes (antimicrobial resistance or antibiotic resistance or antimicrobial susceptibility)

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Development of in vitro and in vivo evaluation of mucoadhesive in-situ gel for intranasal delivery of vinpocetine

That does not make it unsafe or unusual (doctors prescribe it off-label routinely), but you should know what you are signing up for