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A highly unusual thioester bond in a pilus adhesin is required for efficient host cell interaction
After the resolution of the deficiency, if patients show clinical or hematologic signs associated with polycythemia vera, it is recommended they undergo further evaluations
Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation
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