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Both TR and undergo posttranslational modification by sumoylation, which is essential for positive and negative gene regulation by TH, including genes important for metabolic regulation (159)

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Biochem Biophys Acta

A 1-year randomized controlled trial in 130 Alzheimer's patients found that ALCAR treatment (dosage not specified in abstract) resulted in slower rates of deterioration across 13 of 14 outcome measures, with statistical significance achieved for memory, intelligence, attention, and functional scales

Genazzani, A

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