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Without adequate protection, pepsin would cleave the bonds between its amino acids, rendering it inert

Because B12 is water-soluble, excess is excreted by the body

The primary reasons for the low productivity of the producing strains that are now available are the inhibition of the cbi operon and cysG by the cobalamin riboswitch and other downregulating mechanisms

Schipper HM

We've been quietly trying to figure them out for a year

Ghigo E, Goffi S, Nicolosi M, Arvat E, Valente F, Mazza E, et al
