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Radikal bebas dan stres oksidatif tidak hanya merusak protein tetapi juga menyerang DNA, yang menyebabkan mutasi gen dan bahkan kanker

Both the oxidation of nutrients in the mitochondria and the oxidation of nascent proteins in the ER generate toxic reactive oxygen species (ROS): in the mitochondria by electron leakage during oxidative phosphorylation (Murphy, 2009), and in the ER by catalysis of disulfide bond formation by ER oxidoreductase (ERO1) (Higa & Chevet, 2012)

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Kunz, S

Med Hypotheses 18, 351370