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10.1186/s11658-020-00205-0 178 LiuY.WangW.LiY.XiaoY.ChengJ.JiaJ

: Off Label Pseudophakic patients with glaucoma (Schmidt et al 2010) A 2010 study (Schmidt et al, 2010) concluded that echothiophate may be effective in lowering IOP in patients with advanced glaucoma that have had previous cataract surgery to replace their eye's natural cloudy lens with a clear aritificial intraocular lens (pseudophakic patients), and for whom maximal medical therapy with newer class medications provides insufficient lowering of IOP

doi: 10.1016/s0014-5793(03)00641-0 58 NieHYiW

Then, they have validated key findings in vitro and in vivo in Cftr -KO mice and ex vivo in CF patient-derived endothelial cells

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Clinical trials have demonstrated that Huangqi Capsule, in combination with an iodine-restricted diet, can significantly decrease TPOAb and TGAb titers compared to diet alone in HT patients, providing valuable human data