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Table 1 Candidate biomarkers for gut barrier damage in colorectal carcinogenesis
Accelerated age-related decrease in brain-derived neurotrophic factor levels in bipolar disorder

Managing DPN remains challenging due to its complex and poorly understood pathophysiology, varied clinical manifestations, and underdeveloped staging [23,174]
While the introductory overview touches on these, a more granular examination of the involved signaling cascades reveals a multi-pronged mechanism that researchers aim to exploit