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GGT, NEURODEGENERATIVE DISORDERS, AND DEMENTIA Increased oxidative stress - due to excessive production of reactive species or insufficient antioxidant defense - is an important player in the pathophysiology of neurodegenerative disorders, damage to brain cells, and dementia [71]

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Cysteine is synthesized via the transsulfuration pathway, in which homocysteine is first converted to cystathionine by cystathionine-beta-synthase (CBS) and subsequently to cysteine