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However, since there are relatively few cells in the degenerated IVD and cell viability is impaired, stimulation of the remaining cells may be insufficient to achieve repair [13]

It is not a toxicity concern but an efficacy consideration

The bottoms of each rat's feet were painted with black ink (Parker Quink) and the rat was placed in a Plexiglas straight maze (length x width x height: 1 16 x 7,6 x 10 cm)

Gut (2019) 68(9):162432

A man-made electrical suit that our bodies havent really had a chance to evolve to deal with
At 5,200 meters above sea level, we stand at one of the planets most spectacular natural viewpoints