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The result is skin that appears brighter and more uniform not because of surface-level bleaching, but because the underlying biochemistry has shifted

Kohn, A

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By contrast, the ACP does not provide a clear recommendation for urate-lowering therapy (ULT) for patients with frequent, recurrent flares or those with tophi, nor does it recommend monitoring serum urate levels of patients prescribed ULT
This depends on why you started supplementation

Cardiovasc Drugs Ther 25:451459 Evcimen ND, King GL (2007) The role of protein kinase C activation and the vascular complications of diabetes
