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Treatment of Leber's optic atrophy

Paraesthesia (pins and needles) in the hands and feet often improves within two to four weeks, though complete resolution may take several months

It may cause symptoms related to neurological failure like loss of feeling or sensation, irregular bowel movements, sleep disorder, getting irritated, feeling depressed, memory loss, Alzheimer's disease

Vitamin B12 : Boosts energy metabolism and prevents fatigue, allowing individuals to maintain an active lifestyle despite caloric restriction

The case-control studies both scored six, indicating high-quality studies with a moderate risk of bias (Table 4)

Yet, important questions remain - what is the mechanism of action by which MMA exerts its effects in CD8 + T cells