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The plasmid pTrc99A was used as backbone and the previously identified genes for the pathway (TMLH, HTMLA, TMABADH.1S, and BBH.2

The VPA -oxidation metabolite 2-en-VPA is another agent that can promote cerebral oedema when it accumulates in brain and plasma

Virmani, M

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(PubMed) Matalliotakis I, Koumantaki Y, Evageliou A, Matalliotakis G, Goumenou A, Koumantakis E
