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Lesions are restricted to the CNS and are most prevalent in the cerebellum and white matter of the spinal cord, as demyelinating leukoencephalomyelitis

Therefore, we assessed endothelial barrier function, indicated by monolayer HUVEC permeability and cell-tight junction integrity

We also looked for expression of genes involved in the synthesis of melatonin, namely Aanat and Asmt , but again found that although these are expressed in both the mouse and human lung, they were not found to be detected in ILC2 of either species ( Supplementary Figures 3AD )

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Exogenous supplementation of CoQ 10 is safe and does not affect its endogenous biosynthesis [181]

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