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Sometimes it can make it difficult to conceive, but if you are deficient when you are pregnant there is a risk of your baby being born with spina bifida or another neural tube defect called encephalocele

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Nausea, vomiting, diarrhea, constipation, and decreased appetite have all been reported, with frequency and severity dependent on dose and titration schedule

Wittmeyer, J., Saha, A

Malnutrition in cirrhotic patients is characterized by the loss of skeletal muscle and lean body mass (sarcopenia), adipose (fat) tissue (adipopenia), or both (hepatic cachexia), and does not respond to adequate dietary intake of fats or protein

Those with digestive disorders should be particularly cautious, as many commercial detox formulas contain stimulant laxatives that can worsen symptoms and cause dangerous electrolyte imbalances with prolonged use