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The gut microbiota influences levels of bile acids, and AD patients have altered bile acid profiles in serum and cerebrospinal fluid (with higher ratios of toxic vs

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OAT4 interacts with NHE3 and sodium dicarboxylate transporter 1 to participate in the maintenance of intracellular -ketoglutarate ( Mutation Loci of the OAT4 ( SLC22A11 ) Gene SLC22A11 rs2078267 is associated with gout in some Europeans (van der Harst et al., 2010