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In addition to redox-sensitive modifications, increasing evidence suggests EAAT dysfunction in the context of Pb exposure may involve complex interactions between oxidative stress, calcium signaling, and astrocyteneuron communication

It operates in tissues such as the liver, kidney, and heart

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Sarkar, R., Bansal, S

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Cysteine is a semi-essential amino acid and a rate-limiting substrate for intracellular synthesis of G-SH (glutamate and glycine are also taken up by the cells, but they may be supplied by the products of glycolysis or citric acid cycle as well)