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The superoxide produced by NOX can increase NF-B transcription, thereby creating another amplifying loop of pro-inflammatory signaling [69]
The designed sequences were synthesized directly by the company and transformed under the control of different promoters in the vectors
In another study on PD patients and healthy controls based on NM-MRI, there was significant reduction in the lateral, central, and medial appearance of the NM high-intensity signals in the SN in patients with early PD (Wang et al., 2018)
