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Despite correcting his severe B12 and iron deficiency with supplementation, this child remained delayed 7 months after treatment and upon MRI, still showed signs of inadequate myelination, suggesting that he may never achieve full neurological function

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Peripheral nerves depend on tiny blood vessels called vasa nervorum for their oxygen and nutrient supply

Storage: Proper storage of the mixed solution is vital

The final predicted expression of both CBS OPT and L2HGDH OPT were MYPYDVPDYALQISCBS OPT (or L2HGDH OPT )DYKDDDDKKSRGPGRATGAAANSAVDGTAGPGSTGSRVDGSGEGRGSLLTCGDVEENPGP (with the features: HA tag, amino acid linker 1, CBS OPT (or L2HGDH OPT ), FLAG, amino acid linker 2, T2A self-cleavage site, in the order of N to C terminal) (#230088 and #230089, Addgene)

References Pollard, B., & Pomfrett, C