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Once released, B-12 combines with a substance called intrinsic factor (IF) before it is absorbed into the bloodstream

A deficiency in methionine synthase function arising from mutations in its gene, known as MTR, gives rise to what is termed a CblG defect

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10.1371/journal.pmed.1000097 [DOI] [PMC free article] [PubMed] [Google Scholar] NIHR (2025)

That offers many people a chance to manage this condition, meaning they can live longer and with fewer restrictions or impacts from the related conditions and symptoms

Treatment plans at Family Health Care are tailored to fit each patients unique needs
