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Therefore, the dose may need to be lowered for these patients [102,103]

However, our previous study suggested that salivary cortisol levels were a reliable surrogate marker for plasma cortisol 1

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However, human clinical trials are still limited, and optimal dosing in humans has not been formally established

[DOI] [PubMed] [Google Scholar] Pouleur AC, Anker S, Brito D, Brosteanu O, Hasenclever D, Casadei B, Edelmann F, Filippatos G, Gruson D, Ikonomidis I, et al

The dose stays constant for all 10 days of the cycle
