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4.3.4 Possible side effects and potential health risks While probiotics are generally safe, they can cause adverse reactions, including bacterial and fungal sepsis, immune system hyperstimulation, microbial resistance, and gastrointestinal issues, especially in vulnerable populations like premature infants and immunocompromised individuals (Sotoudegan et al., 2019)

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doi: 10.1038/sj.bjp.0701784 154 MizutaniKIkedaKKawaiYYamoriY

Case studies, such as the effectiveness of oral tranexamic acid in treating melasma, further illustrate the practical applications of understanding skin discoloration