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Abstract LB-326: The role of HER3 in HER2-amplified cancers other than breast cancers

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In section II.E

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Tumor CellIntrinsic p38 MAPK signaling promotes IL1-Mediated stromal inflammation and therapeutic resistance in pancreatic cancer [J]

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AGE and SAC Scavenge Reactive Oxygen Species SAC contains a thiol group responsible of its antioxidant capacity because this nucleophile can easily donate its proton to an electrophilic species, thereby neutralizing them or making them less reactive

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Dehydration Proper hydration is essential for overall health and the effectiveness of glutathione supplementation

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Glutathione keeps cells in a reduced state, acting as electron donor for other antioxidative enzymes too, and as a source for the formation of conjugates with some harmful endogenous and xenobiotic compounds, via GSTs catalysis

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