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22 : 40454048 Goldberg SF, Miele ME, Hatta N, Takata M, Paquette-Straub C, Freedman LP and Welch DR (2003) Melanoma metastasis suppression by chromosome 6: evidence for a pathway regulated by CRSP3 and TXNIP
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Furthermore, targeting regulators within the crosstalk itself, such as knocking down deltex E3 ubiquitin ligase 2 to stabilize NCOA4 and promote ferritinophagy, can mitigate cisplatin resistance in NSCLC (121)
However, long-term metformin treatment might promote NAFLD progression in leptin-insensitive individuals [96]

Kidney Blood Pressure Res 42(4):664675 Lee MY, Shim MS, Kim BH, Hong SW, Choi R, Lee EY, Nam SM, Kim GW, Shin JY, Shin YG, Chung CH (2011) Effects of spironolactone and losartan on diabetic nephropathy in a type 2 diabetic rat model
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