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The proposed explanation suggests that metformin candecrease mitochondrial ROS production by inhibiting of respiratory chain complex I, activate the DNA repair pathway through AMPK activation, and reverse the upregulation of NADPH oxidases such as NOX4 and DUOX1/2 induced by radiation

It promotes actin polymerization , a process essential for rebuilding damaged tissue and improving flexibility

* Correspondence: Yanyan Cao [email protected] Li Ma [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Comparative effects of meditation and exercise on physical and psychosocial health outcomes: a review of randomized controlled trials