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These revealed a highly electropositive uptake region formed by TM3, TM5, and TM6 27 , without elucidating further details regarding cargo transport, as it has only been observed in the inward-open configuration

Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with positron emission tomography
5 Goodsell, D

Wang et al., 2023 H)

doi: 10.1186/s12866-024-03513-z

In human subjects, several studies suggest that high selenium supplementation increases the risk of type 2 diabetes [103, 104], and, in mouse models, increased expression of selenoproteins as well as selenoprotein deficiency was also correlated with metabolic dysregulation [105]
