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[DOI] [PubMed] [Google Scholar] 43.Geilfus C.M., Muhling K.H
Canonical de novo NO synthesis occurs via the oxidation of Larginine by oxygen catalysed by NOS

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Compared to placebo, citicoline was found to improve retinal function and post-retinal neural conduction, evidenced by PERG and VEP measures (88)

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There are various mechanisms/pathways through which drugs like ASMs can cause cell damage, inflammation, hormonal stress, oxidative stress, etc