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A study from Mexico found that children with MS and T2DM, compared to healthy controls, exhibited an increase in facultative anaerobes like enteric and lactic acid bacteria, along with a decrease in obligate anaerobes such as Erysipelatoclostridium , Shaalia , and Actinomyces genera, which may cause loss of gut's hypoxic environment, enhanced gut microbial nitrogen metabolism, and increased generation of pathogen-associated molecular patterns

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