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They act as endocrine disruptors, interfering with sex hormone signaling, and their metabolism involves CYP and UGT enzymes

Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes

GHK-Cu operates by coordinating copper (II) ions and delivering them into cells, where they act as cofactors for vital enzymes

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Antenatal diagnosis Antenatal diagnosis is possible and can be made by: Mutation analysis of chorionic villi (the method of choice if the mutation in the family is known)

Deletion of Maged1 in mice abolishes locomotor and reinforcing effects of cocaine