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Transgenic female mice treated with intranasal GHK-Cu had higher alternation percentages in the Y maze, indicating improved cognitive performance, beginning as early as the second month of treatment (Week 8), and continuing through the third month (Week 12) when the study ended, compared to transgenic mice treated with intranasal saline (Figure 1A)

Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury

Nutr Rev 52 : 383387

The goal is to deposit the peptide into the subcutaneous fat layer, which sits between the skin surface and the underlying muscle

Most published findings on both compounds are from rodent models