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Deficiencies in ADK are associated with characteristic biochemical features of hypermethioninemia, normal levels of homocysteine, and increased SAM and SAH

However, progress in the clinical translation of such drugs remains hindered by factors including insufficient evidence of positive efficacy from human trials, challenges in achieving precise drug dosage control, and inter-individual disease heterogeneity

(October 2008)

During the off period, GH levels return to baseline within 1 to 2 weeks (for no-DAC) or 2 to 3 weeks (for DAC)

A suitable plastic tube adaptor (1 cm) was inserted into an external auditory canal with a plastic tympanometer probe

Efficacy and safety of roxadustat for anemia in patients receiving chemotherapy for nonmyeloid malignancies: a randomized, open-label, active-controlled phase III study