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Clarifying the confusion: Brightening vs
& Swain, M
The NAD + /NADH redox pair modulates gene expression through redox-sensitive transcription factors [9], acts as a precursor of multiple NAD + -dependent enzymes involved in synaptic plasticity and neuronal stress resistance, and regulates crucial signaling pathways related to neuronal survival [10]
Yet, in the body, (1) -tocopherol is preferentially retained in the liver by the binding to -tocopherol transfer protein (-TTP), which incorporates -tocopherol into lipoproteins for delivery to extrahepatic tissues
Brain Res 1775 , 147743 (2022)
used multi-drug resistance protein 2 knockout (MDR2-KO) mice as PSC models and analyzed liver tissues and hepatocyte extracts from wild-type mice
