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Although comparative studies have showed that Hunner lesions patients are older, 86, 87, 101-103 have greater urinary frequency and nocturia, 86, 87, 102, 103 higher ICSI scores, 86, 87, 103 and lower bladder capacity 101, 103 compared to those without Hunner lesion, cystoscopy remains the only reliable way to diagnose the presence or absence of Hunner lesions given the overlaps in clinical symptomatology

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The primary outcome was death from any cause by 90 days following diagnosis

Subsequently, MeCbl donates its methyl group to homocysteine, thereby converting it to methionine (Figure 2) while being reduced back to cobalamin

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