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This is first clinical study demonstrating that a TfR antibody can deliver the enzyme IDS across the BBB into the brain for treatment of Hunter syndrome (mucopolysaccharidosis type II)
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A notable example is Escherichia coli ( E
Liu, Y., et al., Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice
H., & Edden, R
Inhibition of MEK1/2 by U0126 or MEK1/2 knockdown results in increased phosphorylation of AKT and p70S6K1 (Fig
