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While several works, following morphometric analyses, report improvements in axons growth, early remyelination, Schwann cell migration, reduced inflammation, muscle preservation, and NMJ restoration (often with outcomes comparable to autografts in terms of CMAP amplitude, muscle fiber area, and gait recovery) these conclusions derive from the application of different protocols with different end-points, gap lengths, and outcome measures (Supplementary Table 1)

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A second Phase 3 trial, TRANSCEND-T2D-1 (type 2 diabetes population), showed dramatically lower rates: 4.4% at 12 mg

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A., Reuter, V