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Another study found that e-cigarette exposure enhanced airway dilation, mucus secretion and fibrogenesis in COPD mice, which was associated with an increased M2 macrophage phenotype (79)

& Baucom, K

It inhibits the pigment responsible for dark spots and uneven skin tone, leading to a more even complexion and reduced hyperpigmentation

This study reported that the A1298C variant produced opposite effects compared to the C677T variant

In addition, and given its rarity, there are no established guidelines for its management

Muroyama A, Inaka M, Matsushima H, Sugino H, Marunaka Y, Mitsumoto Y
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