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[DOI] [PMC free article] [PubMed] [Google Scholar] Nuber S, Zabel U, Lorenz K, Nuber A, Milligan G, Tobin AB, Lohse MJ, Hoffmann C

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developed a quantitative systems pharmacology model to evaluate VPAinduced hyperammonaemia and used this model to evaluate the use of Lcarnitine in preventing hyperammonaemia in both chronic and acute VPA toxicity

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